Figure 3
Electrostatic surface representations of (a) the HNE complex with 1/2SLPI (ball and stick model), and (b) the PPE:elafin complex around the S1 pocket. Superposed representations of the PPE molecule onto HNE of the X-ray structure HNE:1/2SLPI. The solid surface shows HNE and the meshed surface shows PPE. Comparison of HNE and PPE (purple mesh) around (c) the S1 pocket and (d) the S5 pocket. (e) The sequence alignment between HNE and PPE around the S5 pocket. The conflict residues of PPE with Y68i are shown in the purple square. |