Figure 3
Kaplan–Meier survival curves for F98 glioma-bearing rats after chemoradiotherapy. Survival times in days after tumor implantation have been plotted for untreated animals (crosses), infusion of 127IUdR with osmotic pump 20 mg ml−1 alone (triangles), irradiation alone (single fraction of 15 Gy) (open squares) or in combination with 127IUdR delivered by osmotic pump 20 mg ml−1 (filled squares). IUdR was administered for six days starting seven days after tumor implantation. X-ray dose was delivered in a single fraction on day 14 after tumor implantation. Note: in the IUdR group, two rats died at the anaesthesia and were not included in the analysis. |