Intracerebral delivery of 5-iodo-2′-deoxyuridine in combination with synchrotron stereotactic radiation for the therapy of the F98 glioma

Rousseau, J.; Adam, J.-F.; Deman, P.; Wu, T.-D.; Guerquin-Kern, J.-L.; Gouget, B.; Barth, R.F.; Estève, F.; Elleaume, H.

doi:10.1107/S0909049509016987

Journal of Synchrotron Radiation Journal of
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Figure 5
Tumor growth versus time for the different treatments. Tumor volumes measured using the CT images for a subset of rats in each group. Untreated animals (crosses), n = 11; infusion of ¹²⁷IUdR with osmotic pump 20 mg ml⁻¹ alone (triangles), n = 6; irradiation alone (single fraction of 15 Gy) (open squares), n = 5; or in combination with ¹²⁷IUdR with osmotic pump 20 mg ml⁻¹ (filled squares), n = 5. IUdR was administrated for six days starting seven days after tumor implantation. The line corresponds to an exponential fit of the `untreated group' survival data.

JOURNAL OF
SYNCHROTRON
RADIATION

ISSN: 1600-5775

Volume 16| Part 4| May 2009| Pages 573-581

doi:10.1107/S0909049509016987

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