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Figure 4
Comparison of SR images of carpal bones (panel A) and fifth metacarpal bones (panel B) of the CIA mice according to severity grade. The typical findings of CIA, destructive changes in cartilage and bones (CB, MH, S and *) and marrow invasion of pannus tissue (m), can be seen in the SR and histological images (G3-histo). CB: carpal bones; m: marrow cavity; MH: metacarpal bone head; S: styloid process; *: bone erosion. Scale bars = 1 mm (panel A) and 500 µm (panel B).

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