Figure 2
Data are expressed as the number of γ-H2AX foci per cell plotted against repair time post-irradiation. Each plot represents the mean ± standard errors of two independent replicates at least. HMEC cells and solutions of photoactivatable drugs were exposed to 2 Gy 250 kV X-rays separately. The pre-irradiated drugs solution was applied to culture medium at the indicated post-irradiation times and measured for DSBs at 4 and 24 h. Closed circles and open squares correspond to conditions without and with drugs, respectively. It is noteworthy that the data plots labelled `0 h' are the same as those shown in Fig. 1(b). |