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Figure 3
(a) Representative examples of HDCs observed with γ-H2AX immunofluorescence, stained in green (FITC) and counterstained with DAPI (blue). The nucleus marked by the white arrow was not considered as HDCs. (b) Percentage of HDC as a function of post-irradiation time for each photoactivatable drug irradiated separately and added directly to the culture medium at the indicated times (corresponding γ-H2AX data are shown in Fig. 2[link]). Each plot represents the mean ± standard errors of two independent replicates at least. (c) The percentage of HDC assessed at 0, 10 min, 1 h and 4 h post-irradiation shown in (b) were plotted against the corresponding γ-H2AX data shown in Fig. 1(b)[link]. Dotted lines correspond to linear regression when all data were gathered (r = 0.75).

Journal logoJOURNAL OF
SYNCHROTRON
RADIATION
ISSN: 1600-5775
Volume 18| Part 3| April 2011| Pages 456-463
doi:10.1107/S0909049511006017
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