Figure 4
Schematic representation of the possible drug localization in the lipid membrane. Triangles indicate drug molecules located in the border between the head-group and the tail-group; hexagons indicate drug molecules preferably sitting on top of the lipid bilayer. The lower image shows a drug-induced change in the electron density profile. Vertical dashed lines indicate borders of non-disturbed head-group layer. Arrows indicate a drug-induced shift of the electron density profile. |