Figure 5
Relationship between vessel size and the magnitude of pulmonary vasomotor responses (% change in vessel internal diameter, ID) in ControlB (n = 5), MCTB (n = 5) and MCT+Fluo rats (n = 7) following the administration of (a) ACh (3 µg kg−1 min−1), (b) SNP (5 µg kg−1 min−1), (c) L-NAME (50 mg kg−1) and (d) BQ-123 (1 mg kg−1). Data presented as mean ± SEM. * Significantly different from baseline (*P < 0.05; **P < 0.01). † Significantly different from Control rats (†P < 0.05; ††P < 0.01). BData are reproduced from Schwenke et al. (2011) for comparative purposes. |