Figure 6
Transient changes (% change) in (a) systolic right ventricular pressure (sRVP), (b) heart rate (HR) and (c) mean arterial blood pressure (MABP) in response to: ACh (3 µg kg−1 min−1), SNP (5 µg kg−1 min−1), BQ-123 (1 mg kg−1) and L-NAME (50 mg kg−1) in ControlB (n = 5), MCTB (n = 5) and MCT+Fluox rats (n = 7). Data presented as mean ± SEM. *Significantly different from baseline (*P < 0.05; **P < 0.01). †Significantly different from Control rats (†P < 0.05; ††P < 0.01). §Significantly different from MCT rats (§P < 0.05; §§P < 0.01). BData are reproduced from Schwenke et al. (2011) for comparative purposes. |