Figure 1
High-magnification images of lead dust in the trachea of three live mice (M1–M3) after particle insufflation, assessed using a repeat-imaging study design. The head is to the right and the spine is toward the bottom. The top row of images was taken at baseline, shortly after lead dust was delivered to the airway surface. The bottom row shows approximately the same locations (a) 3 h, (b) 9 h and (c) 25 h later. Imaging typically included the same bone edge (bottom left-hand corner) to help ensure that the same airway region was examined each time. Imaging location is just above the carina and the image dimensions are 1.45 mm × 1.2 mm. Stationary particles are marked in red and (the few) moving particles in white (black circles). |