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![[Figure 6]](mo5098fig6mag.jpg)
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Figure 6
Degradation of braided scaffolds in the injured spinal cord was quantitated by X-ray phase-contrast CT with a synchrotron radiation source. (a–f) Relative mass density maps acquired with X-ray phase-contrast CT on 0 (a, d), 7 (b, e) and 28 (c, f) days after implantation. Three-dimensional (a–c) and coronal two-dimensional (d–f) images acquired with X-ray phase-contrast CT revealed that the density of the scaffold gradually decreased in the spinal cord. At 7 and 28 days after implantation the density in the central portion of the scaffold was higher than that in the end portion, indicating faster degradation in the peripheral portion. Centre and end labels in (a) represent the central and end portions of the scaffold, respectively. (g) The X-ray refractive index difference from saline (Δδ value) and estimated mass density through the spinal cord from α to β [described in panels (d)–(f)] at 0 (blue), 7 (red) and 28 (green) days after implantation. Note the densities of the scaffold gradually decreased in the spinal cord. (h) Mass density in the central and end portions of the scaffold after implantation into the spinal cord. *p < 0.01. Values are means ± SEM. Scale bar = 500 µm. |
![[Figure 6]](mo5098fig6.jpg)
 | JOURNAL OF SYNCHROTRON RADIATION |
ISSN: 1600-5775
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