Figure 8
(a) Mean isotropic B-factor (Å2) for each chain of the C.Esp1396I complex (A to D for protein monomers, E and F for DNA single strands) against dose (MGy), normalized to the B-factor of the first dataset for each chain, respectively. Data points are linearly fitted for each chain. Green and purple shaded areas denote 90% confidence intervals on the intercepts and slopes for chains C and F, respectively (other chain confidence intervals are not shown in the interests of clarity). (b) Correlation of the average rate of isotropic B-factor increase (Å2 MGy−1) with the average rate of electron density loss (electrons Å−3 MGy−1). Grey/blue scatter points indicate protein/DNA specific damage sites, respectively. |