Figure 1
Configuration used to acquire images of local lung tissue expansion whilst applying forced oscillations at the airway opening. Coherent synchrotron radiation was directed through the subject impinging on a scintillator. As the X-rays were imparted onto the scintillator they were converted to visible light and directed towards a high-speed detector (PCO Edge 4.2). The detector utilized highly sensitive sCMOS technology to achieve high frame rates with low noise. The speaker and wave tube, used for imparting pressure oscillations into the respiratory system of the mice, is shown in the upper middle section of the figure. |