Analysis of the microvascular morphology and hemodynamics of breast cancer in mice using SPring-8 synchrotron radiation microangiography

Torii, M.; Fukui, T.; Inoue, M.; Kanao, S.; Umetani, K.; Shirai, M.; Inagaki, T.; Tsuchimochi, H.; Pearson, J.T.; Toi, M.

doi:10.1107/S1600577517008372

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Figure 3
Comparison of morphological parameters of microvessels between normal and MDAMB231 mice. (a) The number of branches of each branch order is relative to the A0 origin and shows branches as an A0 ratio. There were A8 branches in MDAMB231, but only A7 branches in normal tissue (normal: n = 6; MDAMB231: n = 7). (b) The proportion of mice with more than A6 branches and less than A5 branches. Mice with more than A6 branches were 2 out of 6 (33.3%) in normal mice and 8 out of 13 (61.5%) in MDAMB231. (c) There was no significant difference in vessel diameter (normal: n = 6; MDAMB231: n = 13). The asterisk (*) indicates that a segment was not observed. The error bars show SD of the mean branch ratio in (a) and mean absolute internal diameter in (c). The absence of error bars in (a) indicates that all animals showed the same change in branch ratio and therefore there is zero error.

JOURNAL OF
SYNCHROTRON
RADIATION

ISSN: 1600-5775

Volume 24| Part 5| September 2017| Pages 1039-1047

https://doi.org/10.1107/S1600577517008372

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