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Figure 1
The structure of PPLO. (a) Stereoview of the dimer of PPLO with the newly identified cross-link and entrance to the active site indicated. The monomers are coloured orange and blue. The Cu atom is shown as a cyan sphere. (b) Order and disorder at the active site. Stereoview of unbiased OMIT electron density for the TPQ quinone ring and the imidazolium ion contoured at 9σ (magenta), 5σ (green), 2.5σ (olive) and final 2FoFc electron density contoured at 2.75σ (blue). The TPQ side chain is shown in its standard on-copper and off-copper conformations. The TPQ beyond the Cβ atom was not included in the refined model (see text).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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