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![[Figure 2]](en5210fig2mag.jpg)
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Figure 2
A structure-based sequence alignment of the ENR enzymes from P. falciparum, P. knowlesi, P. vivax, P. chabaudi, P. yoelii, B. napus, E. coli, M. tuberculosis and T. gondii. The elements of secondary structure and the sequence numbering, which is from the start of the mature enzyme for the P. falciparum and T. gondii enzymes, are shown above and below the alignment, respectively, with cylinders representing α-helices and arrows β-strands. Residues fully conserved in the above sequences are shown in black boxes and residues which are within 4 Å of the inhibitor triclosan are highlighted by a black circle. Those residues which form the conserved SGE motif (residues 238–240 in TgENR) are enclosed by a black box. |
![[Figure 2]](en5210fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
