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Figure 5
Contoured maps of Rfree (blue contours) and −LLfree (red) showing bivariate dependence on WBiso and WX-ray for the AMPK structure (PDB code 2uv4 ). For Rfree, the contour levels are 0.00010, 0.00016, 0.00025, 0.00040, 0.00063, 0.0010 and 0.0016 above the global minimum value (0.2071, marked with a blue cross at WBiso = 0.29, WX-ray = 0.95); for −LLfree the contour levels are 0.10, 0.16, 0.25, 0.40, 0.63, 1.0, 1.6, 2.5, 4.0, 6.3 and 10 above the global minimum value (7421.9, marked with a red cross at WBiso = 0.17, WX-ray = 1.40).

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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