Sequence alignment of StGE2 (PDB entry 4g4g
) with the best sequence and structural homologues: Cip2_GE (the closest sequence and structural homologue, with 56% identity over 97% sequence coverage and a Z-score of 59.1; PDB entry 3pic
; Pokkuluri et al., 2011), 2,6-dihydroxy-pseudo-oxynicotine hydrolase (the second closest sequence homologue, with 28% identity over 37% sequence coverage and a Z-score of 16.2; PDB entry 2jbw
; Schleberger et al., 2007), putative acetylxylan esterase (a structural homologue with a Z-score of 18.8; PDB entry 3nuz
; Joint Centre for Structural Genomics, unpublished work) and SusD/RagB-associated esterase-like protein (a structural homologue with a Z-score of 18.8; PDB entry 3g8y
; Joint Centre for Structural Genomics, unpublished work). Identical and similar residues are shown in white on a red background and in red on a white background, respectively. The disulfide bonds (numbers in green) and the residues of interest (cyan triangles) are also indicated on the same line. The secondary-structure elements α-helices, 310-helices, β-strands and strict β-turns are denoted H, G, S and TT, respectively.