Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding

Oganesyan, V.; Mazor, Y.; Yang, C.; Cook, K.E.; Woods, R.M.; Ferguson, A.; Bowen, M.A.; Martin, T.; Zhu, J.; Wu, H.; Dall'Acqua, W.F.

doi:10.1107/S1399004715018015

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

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Figure 7
Three-dimensional views of the FcγRI–Fc (green/orange) complex in relation to the presence of Fab arms. (a) shows a view in which the Fab arms would be positioned towards the viewer, whereas (b) shows a view in which the Fab arms would point towards the right side. The N-terminus of both Fc polypeptides points away from FcγRI, which allows the presence of the corresponding Fab arms.

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 71| Part 11| October 2015| Pages 2354-2361

doi:10.1107/S1399004715018015

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