Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD

Bent, A.F.; Mann, G.; Houssen, W.E.; Mykhaylyk, V.; Duman, R.; Thomas, L.; Jaspars, M.; Wagner, A.; Naismith, J.H.

doi:10.1107/S2059798316015850

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 1
Synthesis schematic of the two-step process to form thiazoles and oxazoles in cyanobactins. The initial step is the ATP-dependent PatD reaction to the form thiazolines and oxazoline, followed by FMN-dependent oxidation by PatGox to yield thiazoles. Note that in related pathways the oxazolines are also oxidized to oxazole rings.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 72| Part 11| November 2016| Pages 1174-1180

https://doi.org/10.1107/S2059798316015850

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