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![[Figure 1]](ag5007fig1mag.jpg)
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Figure 1
Evolution of the SBP c-clamp. The general structure of an SBP is a c-clamp. The c-clamp has undergone significant structural evolution. The conformational range that this structure can occupy includes a compact cleft resembling a stone (PDB entry 1xvx; Shouldice et al., 2005  ), an elongated cleft resembling a dumbbell (PDB entry 4wed; New York Structural Genomics Research Consortium, unpublished work) and clefts with more curvature that resemble horseshoes (PDB entries 2xy4 and 5cr9; Ilari et al., 2011; Midwest Center for Structural Genomics, unpublished work). Models for each morphology are included below the respective PDB codes. If a structure is metal-bound, the metal sphere is shown and is colored by CPK chemical convention. |
![[Figure 1]](ag5007fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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