forthcoming articles
The following articles are a selection of those recently accepted for publication in Acta Crystallographica Section D: Structural Biology.
See also Forthcoming articles in all IUCr journals.
research papers
Michaelis-like complex of mouse ketohexokinase isoform C
Thee structure of ketohexokinase C in complex with a natural substrate and product ADP mimicking the Michaelis complex is reported and a comparison with other structures with and without ligands shows that it undergoes a conformational change that places the enzyme into a catalytically competent form. These findings will be of interest to those in the area of enzymology, enzyme structure–function and drug discovery.
research papers
research papers
Identifying and avoiding radiation damage in macromolecular crystallography
This review covers the symptoms of radiation damage in macromolecular crystallography, how to avoid accruing radiation damage during data collection and how to identify and correct for radiation-damage artefacts in a solved structure.
research papers
A database overview of metal-coordination distances in metalloproteins
Through the analysis of more than 115 000 metal-binding sites in metalloproteins, experimentalists are offered useful reference data that improve the understanding of metal-binding interactions and protein coordination. Carboxylate coordination, which is common for a variety of metals, is especially highlighted.