The geometric parameters of the title compound, C
11H
10ClNO
2, are in the normal ranges. The phthalimide moiety is planar and the chloropropyl chain adopts a synclinal conformation. The crystal packing is stabilized by two intermolecular C—H
O contacts.
Supporting information
CCDC reference: 270289
Key indicators
- Single-crystal X-ray study
- T = 173 K
- Mean (C-C) = 0.002 Å
- R factor = 0.029
- wR factor = 0.074
- Data-to-parameter ratio = 16.7
checkCIF/PLATON results
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Data collection: X-AREA (Stoe & Cie, 2001); cell refinement: X-AREA; data reduction: X-AREA; program(s) used to solve structure: SHELXS97 (Sheldrick, 1990); program(s) used to refine structure: SHELXL97 (Sheldrick, 1997); molecular graphics: PLATON (Spek, 2003); software used to prepare material for publication: SHELXL97 and PLATON.
2-(3-Chloropropyl)-2,3-dihydro-1
H-isoindole-1,3-dione
top
Crystal data top
C11H10ClNO2 | F(000) = 464 |
Mr = 223.65 | Dx = 1.393 Mg m−3 |
Monoclinic, P21/n | Mo Kα radiation, λ = 0.71073 Å |
Hall symbol: -P 2yn | Cell parameters from 29481 reflections |
a = 4.5421 (4) Å | θ = 3.7–27.1° |
b = 15.3996 (15) Å | µ = 0.34 mm−1 |
c = 15.3471 (13) Å | T = 173 K |
β = 96.605 (7)° | Rod, colourless |
V = 1066.35 (17) Å3 | 0.38 × 0.22 × 0.22 mm |
Z = 4 | |
Data collection top
Stoe IPDS-II two-circle diffractometer | 2290 independent reflections |
Radiation source: fine-focus sealed tube | 2103 reflections with I > 2σ(I) |
Graphite monochromator | Rint = 0.033 |
ω scans | θmax = 26.9°, θmin = 4.2° |
Absorption correction: multi-scan (MULABS; Spek, 2003; Blessing, 1995) | h = −5→5 |
Tmin = 0.883, Tmax = 0.930 | k = −19→19 |
11334 measured reflections | l = −19→19 |
Refinement top
Refinement on F2 | Secondary atom site location: difference Fourier map |
Least-squares matrix: full | Hydrogen site location: inferred from neighbouring sites |
R[F2 > 2σ(F2)] = 0.029 | H-atom parameters constrained |
wR(F2) = 0.074 | w = 1/[σ2(Fo2) + (0.0343P)2 + 0.3497P] where P = (Fo2 + 2Fc2)/3 |
S = 1.06 | (Δ/σ)max = 0.001 |
2290 reflections | Δρmax = 0.24 e Å−3 |
137 parameters | Δρmin = −0.18 e Å−3 |
0 restraints | Extinction correction: SHELXL, Fc*=kFc[1+0.001xFc2λ3/sin(2θ)]-1/4 |
Primary atom site location: structure-invariant direct methods | Extinction coefficient: 0.064 (5) |
Special details top
Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes)
are estimated using the full covariance matrix. The cell e.s.d.'s are taken
into account individually in the estimation of e.s.d.'s in distances, angles
and torsion angles; correlations between e.s.d.'s in cell parameters are only
used when they are defined by crystal symmetry. An approximate (isotropic)
treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s.
planes. |
Refinement. Refinement of F2 against ALL reflections. The weighted R-factor
wR and goodness of fit S are based on F2, conventional
R-factors R are based on F, with F set to zero for
negative F2. The threshold expression of F2 >
σ(F2) is used only for calculating R-factors(gt) etc.
and is not relevant to the choice of reflections for refinement.
R-factors based on F2 are statistically about twice as large
as those based on F, and R- factors based on ALL data will be
even larger. |
Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2) top | x | y | z | Uiso*/Ueq | |
N1 | 0.6964 (2) | 0.41164 (6) | 0.34142 (6) | 0.0229 (2) | |
C1 | 0.6132 (3) | 0.49803 (7) | 0.35304 (7) | 0.0235 (2) | |
O1 | 0.7167 (2) | 0.54462 (6) | 0.41289 (6) | 0.0350 (2) | |
C2 | 0.3783 (2) | 0.51770 (7) | 0.27916 (7) | 0.0226 (2) | |
C3 | 0.3292 (3) | 0.44286 (7) | 0.22848 (7) | 0.0228 (2) | |
C4 | 0.5321 (3) | 0.37354 (7) | 0.26842 (7) | 0.0238 (2) | |
O2 | 0.5576 (2) | 0.29839 (6) | 0.24564 (6) | 0.0363 (2) | |
C5 | 0.2224 (3) | 0.59374 (8) | 0.25816 (8) | 0.0294 (3) | |
H5 | 0.2570 | 0.6447 | 0.2927 | 0.035* | |
C6 | 0.0114 (3) | 0.59226 (8) | 0.18383 (8) | 0.0322 (3) | |
H6 | −0.1000 | 0.6431 | 0.1677 | 0.039* | |
C7 | −0.0375 (3) | 0.51736 (9) | 0.13318 (8) | 0.0330 (3) | |
H7 | −0.1816 | 0.5182 | 0.0832 | 0.040* | |
C8 | 0.1218 (3) | 0.44088 (8) | 0.15460 (8) | 0.0299 (3) | |
H8 | 0.0893 | 0.3899 | 0.1201 | 0.036* | |
C9 | 0.9129 (2) | 0.36446 (8) | 0.40201 (7) | 0.0239 (2) | |
H9A | 1.0683 | 0.4051 | 0.4275 | 0.029* | |
H9B | 1.0093 | 0.3191 | 0.3695 | 0.029* | |
C10 | 0.7639 (3) | 0.32230 (8) | 0.47571 (8) | 0.0270 (3) | |
H10A | 0.6754 | 0.3684 | 0.5094 | 0.032* | |
H10B | 0.6010 | 0.2845 | 0.4495 | 0.032* | |
C11 | 0.9747 (3) | 0.26860 (8) | 0.53830 (8) | 0.0309 (3) | |
H11A | 0.8728 | 0.2509 | 0.5891 | 0.037* | |
H11B | 1.1479 | 0.3046 | 0.5605 | 0.037* | |
Cl1 | 1.10135 (7) | 0.172293 (19) | 0.48487 (2) | 0.03125 (12) | |
Atomic displacement parameters (Å2) top | U11 | U22 | U33 | U12 | U13 | U23 |
N1 | 0.0252 (5) | 0.0211 (5) | 0.0212 (4) | 0.0003 (4) | −0.0021 (4) | −0.0005 (4) |
C1 | 0.0269 (6) | 0.0213 (5) | 0.0221 (5) | −0.0023 (4) | 0.0024 (4) | −0.0005 (4) |
O1 | 0.0446 (5) | 0.0268 (5) | 0.0309 (5) | −0.0029 (4) | −0.0076 (4) | −0.0084 (4) |
C2 | 0.0248 (5) | 0.0213 (5) | 0.0217 (5) | −0.0018 (4) | 0.0030 (4) | 0.0004 (4) |
C3 | 0.0245 (5) | 0.0218 (5) | 0.0217 (5) | −0.0010 (4) | 0.0017 (4) | 0.0003 (4) |
C4 | 0.0281 (6) | 0.0219 (5) | 0.0208 (5) | −0.0008 (4) | 0.0005 (4) | −0.0014 (4) |
O2 | 0.0509 (6) | 0.0222 (4) | 0.0330 (5) | 0.0051 (4) | −0.0072 (4) | −0.0065 (4) |
C5 | 0.0357 (6) | 0.0227 (6) | 0.0299 (6) | 0.0030 (5) | 0.0039 (5) | 0.0006 (5) |
C6 | 0.0327 (6) | 0.0295 (6) | 0.0340 (6) | 0.0075 (5) | 0.0027 (5) | 0.0082 (5) |
C7 | 0.0305 (6) | 0.0388 (7) | 0.0280 (6) | 0.0023 (5) | −0.0040 (5) | 0.0060 (5) |
C8 | 0.0318 (6) | 0.0302 (6) | 0.0260 (6) | −0.0003 (5) | −0.0039 (5) | −0.0020 (5) |
C9 | 0.0228 (5) | 0.0262 (6) | 0.0220 (5) | 0.0016 (4) | −0.0009 (4) | 0.0028 (4) |
C10 | 0.0289 (6) | 0.0262 (6) | 0.0266 (6) | 0.0012 (5) | 0.0056 (5) | 0.0022 (4) |
C11 | 0.0441 (7) | 0.0245 (6) | 0.0232 (5) | −0.0019 (5) | −0.0004 (5) | 0.0014 (4) |
Cl1 | 0.03304 (18) | 0.02180 (17) | 0.03661 (19) | 0.00249 (11) | −0.00583 (12) | −0.00026 (11) |
Geometric parameters (Å, º) top
N1—C1 | 1.4001 (15) | C6—H6 | 0.9500 |
N1—C4 | 1.4015 (14) | C7—C8 | 1.4015 (18) |
N1—C9 | 1.4660 (14) | C7—H7 | 0.9500 |
C1—O1 | 1.2165 (14) | C8—H8 | 0.9500 |
C1—C2 | 1.4958 (15) | C9—C10 | 1.5280 (16) |
C2—C5 | 1.3871 (16) | C9—H9A | 0.9900 |
C2—C3 | 1.3939 (15) | C9—H9B | 0.9900 |
C3—C8 | 1.3885 (16) | C10—C11 | 1.5203 (17) |
C3—C4 | 1.4949 (16) | C10—H10A | 0.9900 |
C4—O2 | 1.2183 (15) | C10—H10B | 0.9900 |
C5—C6 | 1.4029 (18) | C11—Cl1 | 1.8198 (13) |
C5—H5 | 0.9500 | C11—H11A | 0.9900 |
C6—C7 | 1.3943 (19) | C11—H11B | 0.9900 |
| | | |
C1—N1—C4 | 111.89 (9) | C8—C7—H7 | 119.4 |
C1—N1—C9 | 124.14 (9) | C3—C8—C7 | 117.16 (11) |
C4—N1—C9 | 123.80 (9) | C3—C8—H8 | 121.4 |
O1—C1—N1 | 124.76 (11) | C7—C8—H8 | 121.4 |
O1—C1—C2 | 129.26 (11) | N1—C9—C10 | 111.00 (9) |
N1—C1—C2 | 105.99 (9) | N1—C9—H9A | 109.4 |
C5—C2—C3 | 121.58 (11) | C10—C9—H9A | 109.4 |
C5—C2—C1 | 130.37 (11) | N1—C9—H9B | 109.4 |
C3—C2—C1 | 108.05 (10) | C10—C9—H9B | 109.4 |
C8—C3—C2 | 121.59 (11) | H9A—C9—H9B | 108.0 |
C8—C3—C4 | 130.34 (11) | C11—C10—C9 | 113.48 (10) |
C2—C3—C4 | 108.07 (9) | C11—C10—H10A | 108.9 |
O2—C4—N1 | 124.58 (11) | C9—C10—H10A | 108.9 |
O2—C4—C3 | 129.44 (10) | C11—C10—H10B | 108.9 |
N1—C4—C3 | 105.98 (9) | C9—C10—H10B | 108.9 |
C2—C5—C6 | 117.25 (11) | H10A—C10—H10B | 107.7 |
C2—C5—H5 | 121.4 | C10—C11—Cl1 | 111.55 (8) |
C6—C5—H5 | 121.4 | C10—C11—H11A | 109.3 |
C7—C6—C5 | 121.13 (11) | Cl1—C11—H11A | 109.3 |
C7—C6—H6 | 119.4 | C10—C11—H11B | 109.3 |
C5—C6—H6 | 119.4 | Cl1—C11—H11B | 109.3 |
C6—C7—C8 | 121.29 (11) | H11A—C11—H11B | 108.0 |
C6—C7—H7 | 119.4 | | |
| | | |
C4—N1—C1—O1 | 177.96 (11) | C8—C3—C4—O2 | −1.4 (2) |
C9—N1—C1—O1 | 2.39 (18) | C2—C3—C4—O2 | 178.82 (13) |
C4—N1—C1—C2 | −1.47 (12) | C8—C3—C4—N1 | 179.09 (12) |
C9—N1—C1—C2 | −177.04 (10) | C2—C3—C4—N1 | −0.66 (12) |
O1—C1—C2—C5 | 1.7 (2) | C3—C2—C5—C6 | 0.30 (18) |
N1—C1—C2—C5 | −178.95 (12) | C1—C2—C5—C6 | −179.75 (11) |
O1—C1—C2—C3 | −178.39 (12) | C2—C5—C6—C7 | −0.31 (19) |
N1—C1—C2—C3 | 1.00 (12) | C5—C6—C7—C8 | 0.0 (2) |
C5—C2—C3—C8 | −0.03 (18) | C2—C3—C8—C7 | −0.24 (18) |
C1—C2—C3—C8 | −179.98 (11) | C4—C3—C8—C7 | −179.96 (12) |
C5—C2—C3—C4 | 179.75 (11) | C6—C7—C8—C3 | 0.2 (2) |
C1—C2—C3—C4 | −0.21 (12) | C1—N1—C9—C10 | 86.98 (13) |
C1—N1—C4—O2 | −178.16 (12) | C4—N1—C9—C10 | −88.07 (13) |
C9—N1—C4—O2 | −2.58 (19) | N1—C9—C10—C11 | 177.15 (10) |
C1—N1—C4—C3 | 1.35 (13) | C9—C10—C11—Cl1 | −67.71 (12) |
C9—N1—C4—C3 | 176.93 (10) | | |
Hydrogen-bond geometry (Å, º) top
D—H···A | D—H | H···A | D···A | D—H···A |
C11—H11A···O2i | 0.99 | 2.57 | 3.3251 (15) | 133 |
C11—H11B···O1ii | 0.99 | 2.43 | 3.2494 (15) | 140 |
Symmetry codes: (i) x+1/2, −y+1/2, z+1/2; (ii) −x+2, −y+1, −z+1. |