Figure 3
A superposition of the molecular conformations of safinamide molecules. The overlay was made by making a least-squares fit through the central aromatic ring system (C8–C13) of safinamide polymorph (I). The labels and r.m.s. deviations (Å) are as follows: safinamide polymorph (II), 0.012; extracted structure of safinamide from safinamide–human monoamine oxidase complex, (III), 0.025. H atoms have been omitted for clarity. |