Crystal structure of the cytotoxic macrocyclic trichothecene Isororidin A

Asmaey, M.A.; Kalofolias, D.A.; Charavgi, M.-D.; Abdel-Rahim, I.R.; Chrysina, E.D.; Abatis, D.

doi:10.1107/S2053229624006144

Acta Crystallographica Section C
Acta Crystallographica
Section C STRUCTURAL CHEMISTRY

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Figure 1
(a) Schematic representation of the Isororidin A X-ray diffraction solution, drawn with 50% probability displacement ellipsoids. O atoms are shown in red, C atoms in light grey and H atoms in pale pink. The absolute configurations of C6′ (R) and C13′ (S) shown in Scheme 1

are indicated. (b) A view of the intermolecular hydrogen-bond interactions formed between Isororidin A (shown in red) and its symmetry-related molecules [colour code for symmetry codes: (x + $[{1\over 2}]$ , −y + $[{3\over 2}]$ , −z + 1) in lime, (−x + 1, y + $[{1\over 2}]$ , −z + $[{3\over 2}]$ ) in lavender, (x − $[{1\over 2}]$ , −y + $[{1\over 2}]$ , −z + 1) in orange, (x + 1, y, z) in tan and (−x + $[{1\over 2}]$ , −y + 1, z + $[{1\over 2}]$ ) in salmon], while the hydrogen bonding is indicated with blue dashed lines.

STRUCTURAL
CHEMISTRY

ISSN: 2053-2296

Volume 80| Part 8| August 2024| Pages 407-411

https://doi.org/10.1107/S2053229624006144

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