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Figure 2
Multiple sequence alignment of S. cerevisiae GluRS-N (a) and Arc1p-N (b) with orthologous sequences from other yeasts. Shown are the sequences from Yarrowia lipolytica (Yl), Debaryomyces hansenii (Dh), Candida albicans (Ca), Kluyveromyces lactis (Kl), Ashbya gossypii (Ag), Saccharomyces cerevisiae (Sc) (all group 1), Ustilago maydis (Um) and Schizosaccharomyces pombe (Sp) (group 2). Identical residues are shown as white characters in a black box, residues conserved among the sequences of a group are printed in bold and residues conserved among all sequences are shown in a frame. Secondary-structure elements observed in the reported structures of S. cerevisiae Arc1p-N and GluRS-N are represented graphically above the alignment, the consensus sequence is shown below the sequences and the accessibility of residues in the structures is represented schematically by the bar labelled `acc' below the alignment, with accessible residues shown in black, buried residues in white and intermediate residues in grey. |