Everyone is using biological structures, but how does one find the structure(s) one wants?

A comment on how easy (or difficult) it is to find a stucture of interest and some suggestions on what could be done to start to address the problem.

Improving macromolecular structure refinement with metal-coordination restraints

The Crystallography Open Database was mined to extract and organize metal environments. An algorithm and software were designed to apply the derived data to metal-containing components.

The 1.3 Å resolution structure of the truncated group Ia type IV pilin from Pseudomonas aeruginosa strain P1

The structure of a type IV pilin from a human-pathogenic strain of P. aeruginosa was solved to 1.3 Å resolution using molecular replacement with an AlphaFold-generated search model. It is the first structure from this group of pilins to be discussed and reveals the structural differences that result in functional diversity between closely related type IV pili.

Photosystem II: light-dependent oscillation of ligand composition at its active site

Analysis of light-dependent changes in the number of oxygen ligands in the CaMn₄ cluster of the oxygen-evolving center suggests a possible mechanism for O=O bond formation by photosystem II.

Peter Main (1939–2024)

Peter Main is remembered.