Welcoming two new Co-editors

Two new Co-editors are welcomed to Acta Cryst. D – Structural Biology.

The success rate of processed predicted models in molecular replacement: implications for experimental phasing in the AlphaFold era

A large set of SAD-phased PDB depositions were tested for solubility by molecular replacement using AlphaFold2 and other approaches. The 3% of cases that were not solved help to show where experimental phasing efforts could be focused in the future.

EMhub: a web platform for data management and on-the-fly processing in scientific facilities

This article presents EMhub, a web platform designed to support the daily operations of a scientific facility. EMhub enables the easy management of users, instruments, bookings and project tracking. The application was initially developed to meet the needs of a cryoEM facility, but the versatility of its design makes it suitable for extension to other areas.

Structure and stability of an apo thermophilic esterase that hydrolyzes polyhydroxybutyrate

A future involving plastics that can be degraded and resynthesized requires an appropriate plastic to be found, plus green solutions that are compatible with waste-management systems. Here, the structure, stability and substrate-size preference are reported for a recently identified thermophilic serine hydrolase that degrades bioplastics such as polyhydroxybutyrate and other polymers.

Analysis of crystallographic phase retrieval using iterative projection algorithms

The behavior of iterative projection algorithms for crystallographic phase retrieval is systematically investigated. It is shown that information present in the algorithm trajectory following convergence can be exploited to improve the final density estimate.