issue contents
November 2024 issue
Early view articles
CCP4
Open access
A large set of SAD-phased PDB depositions were tested for solubility by molecular replacement using AlphaFold2 and other approaches. The 3% of cases that were not solved help to show where experimental phasing efforts could be focused in the future.
research papers
Open access
This article presents EMhub, a web platform designed to support the daily operations of a scientific facility. EMhub enables the easy management of users, instruments, bookings and project tracking. The application was initially developed to meet the needs of a cryoEM facility, but the versatility of its design makes it suitable for extension to other areas.
Open access
A future involving plastics that can be degraded and resynthesized requires an appropriate plastic to be found, plus green solutions that are compatible with waste-management systems. Here, the structure, stability and substrate-size preference are reported for a recently identified thermophilic serine hydrolase that degrades bioplastics such as polyhydroxybutyrate and other polymers.
PDB reference: apo LtPHBase, 9byu
Open access
The behavior of iterative projection algorithms for crystallographic phase retrieval is systematically investigated. It is shown that information present in the algorithm trajectory following convergence can be exploited to improve the final density estimate.