Figure 1
Sequence alignment of the three SsoPCNA subunits with the single PCNA proteins from Pyrococcus furiosus and Homo sapiens. Highly conserved residues are highlighted in black and conservatively substituted residues in grey. The interdomain-connecting loop (IDCL) is indicated by asterisks, highlighting the three-residue insertion present in SsoPCNA1. The sequence given for SsoPCNA3 is that used in this study and is based on its original annotation in the public database. The second M (residue 16) is probably the correct start site. Accession Nos.: SsoPCNA1, P57766; SsoPCNA2, Q97Z84; SsoPCNA3, P57765; StoPCNA3, Q975N2; P. furiosus PyrfuPCNA, O73947; human PCNA, P12004. |