Figure 2
Ribbon diagram of the LpxC–UDP complex. Domains I and II are shown in green and wheat, respectively. Secondary structure is labelled according to previous assignments (Whittington et al., 2003). UDP is depicted as spheres and myristic acid as sticks. Activity-related Zn2+ ions are depicted as grey spheres, with the inhibitory ion labelled I. Ligand atoms are coloured as follows: C, black; O, red; N, blue; P, yellow. Figs. 2, 3 and 4 were prepared with PyMOL (DeLano, 2002). |