Figure 4
Superposition of glCK (green) and pfCK (gray) showing the environment of the adenine group of ADP. A tyrosine-carrying loop adopts a more closed conformation in pfCK than in glCK such that the tyrosine residue stacks against the adenine ring. A loop that flanks the other side of the adenine ring is partially disordered in the crystal structure of glCK, which does not contain ADP. |