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Figure 3
Mapping of conserved regions onto the TmYeaZ structure. (a) Ribbon representation of TmYeaZ colored by sequence conservation of 237 homologs of TmYeaZ. The most conserved residues are shown in magenta and the least conserved residues in cyan. The most conserved regions of the structure are marked 1, 2 and 3, respectively. (b) Molecular surface of TmYeaZ colored by sequence conservation. The orientation of the molecule is the same as in Fig. 2[link](a). (c) A sequence logo representation of the three most conserved regions in YeaZ. A logo consists of stacks of symbols, one stack for each position in the sequence. The overall height of the stack indicates the sequence conservation at that position, while the height of the symbols within the stack indicates the relative frequency of each amino or nucleic acid at that position. (d, e) Molecular surface of the AB (d) and A2 (or B2) (e) dimers colored by sequence conservation, as in Figs. 1(b) and 1(c).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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