Figure 2
Reston VP30 CTD dimer. (a) Superimposition of the EBOV and RESTV VP30 C-terminal domain structures using a single domain shows a rotation about the dimer interface. The RESTV VP30 molecules are colored orange and yellow, while the EBOV VP30 molecules are colored blue and green. For clarity, the Smt is not illustrated. (b) The altered orientation of the RESTV VP30 CTD buries the basic residues Arg179 and Lys180 in the dimer interface. |