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Figure 1
Purification and crystallization of HCoV-NL63 main protease. (a) SDS–PAGE analysis of purified HCoV-NL63 main protease. The molecular masses of the marker and HCoV-NL63 main protease are indicated in kDa. (b) Typical complex crystals of HCoV-NL63 main protease with inhibitor N3 grown by the hanging-drop method. These crystals with typical dimensions of 0.1 × 0.05 × 0.03 mm were used for subsequent diffraction and data collection.

ISSN: 2053-230X
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