Figure 3
P. falciparum OPRTase crystal packing. PfOPRTase packs with eight molecules in the asymmetric unit. All of the chains are shown in different colors: chains A and B in light orange and dark orange, chains C and D in light green and blue-green, chains E and H in light pink and dark pink and chains F and H in olive and brown, respectively. Catalytic dimers are colored in different shades of the same color. The unit cell is shown with green lines. The N- and C-termini of all chains are labeled. The rotation axis of the catalytic dimer is nearly parallel to the crystallographic axis, which caused the observed pseudo-translation. |