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Figure 6
Host–parasite differences in the active site of OPRTase. Differences in key amino acids are color-coded, with the human enzyme structure in green and the malaria parasite structure in red. The space-filling model depicts the position of the product orotidylate (OMP) from the human OPRTase structure. The amino acids in green are those found within 4 Å of OMP (see §[link]3.3).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 71| Part 5| April 2015| Pages 600-608
doi:10.1107/S2053230X1500549X
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