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Figure 7
Intersubunit inhibitory interactions. (a) Unique, parasite-specific, interdimer contacts involving the potentially inhibitory insertion of a loop from one dimer (green) and the active site of an adjacent dimer (pink). (b) Details of the interdimer contacts showing hydrogen-bond interactions that stabilize the incoming loop (green) and that help to form a defined structure on the open `hood' (Glu85, Phe86 and Ile87). |