Figure 1
(a) LmNMT in cartoon representation bound to the cofactor myristoyl-CoA (C atoms in grey) and the ligand DDD85646 (C atoms in gold; PDB entry 2wsa
; Frearson et al., 2010). (b) shows the orientation of DDD85646 (C atoms in grey) and a fragment hit (C atoms in gold) within the peptide-binding pocket of LmNMT |