Do protein crystals nucleate within dense liquid clusters?

Maes, D.; Vorontsova, M.A.; Potenza, M.A.C.; Sanvito, T.; Sleutel, M.; Giglio, M.; Vekilov, P.G.

doi:10.1107/S2053230X15008997

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 4
The evolution of the characteristic diffusion times of the clusters τ₂ in (a) and (b) and monomers τ₁ in (c) extracted from DLS correlation functions similar to those in Figs. 3

(a), 3

(c), 3

(e) and 3

(g) during the crystallization of lysozyme [50 mg ml⁻¹ in 100 mM sodium acetate buffer pH 4.5 with 30 mg ml⁻¹ (0.51 M) sodium chloride]. The time t is measured from the onset of the experiment. The black line in (a) and (b) depicts the t^0.32 dependence, which is close to the t^0.33 typical of Ostwald ripening.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 71| Part 7| July 2015| Pages 815-822

https://doi.org/10.1107/S2053230X15008997

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