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Figure 7
(a) The theoretical scattering of scMex67LRR-NTF2L–Mtr2 matched the observed SAXS profile for the equivalent ctMex67–Mtr2 construct. (b) The theoretical scattering of the two configurations of the RRM domain present in the crystal structure of scMex67ΔUBA–Mtr2 fitted to varying degrees: configuration 1 (blue) fitted the SAX data well, whereas configuration 2 (red) fitted less well. (c) A range of atomic models of the ctMex67ΔN–Mtr2 were generated by BILBOMD and the three best models had excellent fits to the experimental SAXS profile. The spatial arrangement of the LRR domain relative to the NTF2L domain was conserved between models, whereas the position of the UBA domain was variable.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 71| Part 7| July 2015| Pages 876-888
https://doi.org/10.1107/S2053230X15008766
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