Figure 1
Superimposition of hLN40 and E. coli LN40 (PDB entry 1b62). hLN40 is colored yellow, while the E. coli homolog is colored green. The ATPase and transducer domains are located to the right and left, respectively, of the short loop colored blue. Residues in the ATP-binding loop of hLN40 are colored magenta, while those in E. coli LN40 are colored pink (the loop in the latter is ordered owing to extensive crystal contacts). In hLN40, ADP is depicted in stick representation and Mg2+ is shown as a green sphere. Secondary-structure elements are labelled beginning at the N-terminus, with the first helix being αA and the first β-strand being β1. |