Figure 3
Interactions within the β-sandwich fold. (a) Overview of the hDSPRY structure, with the regions displayed in the enlargements in (b), (c) and (d) highlighted. Residues that are discussed in the manuscript are shown as stick models. (b) Loop D lies in a bowl-like curvature and forms a salt bridge between Arg146 and Asp157. (c) The salt bridge between Glu184 and Lys207 in the loop connecting β10 and β11 is depicted in purple. (d) Cys139 and Cys145 that do not form a disulfide bond are shown. |