Figure 4
Structural comparison of hDSPRY (green) with the SPRY domain of Ash2L (red; PDB entry 3toj
; Chen et al., 2012) using the DALI server (Holm & Rosenström, 2010). Regions that show most significant structural differences are indicated by intense colour shading and are marked by grey circles. The 44-residue loop of Ash2L that is not resolved in the crystal structures is marked with a red circle. Loop D is highlighted in purple. |