Figure 2
Comparison of the domain orientations in the RizA structure with those of other LALs. (a–c) Structural superpositions of RizA (a) with BL00235 (b) and BacD (c). RizA is coloured according to the A-, B- and C-domains (blue, purple and yellow, respectively). BL00235 and BacD are coloured light cyan and light green, respectively. (d–f) Surface representations of RizA (d), BL00235 (e) and BacD (f). For the three proteins, the A-, B- and C-domains are coloured blue, purple and yellow, respectively. ADP (coloured red), divalent ions (Mg2+ or Ca2+, coloured green) and the amino-acid substrate (BacD only, coloured dark blue) bound to BL00235 (g) and BacD (h) are viewed from the same angle as in (e) and (f), respectively. |