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Figure 6
Comparison of the modes of binding of glycolate to Ma21 (blue; PDB entry 4pc8), citrate to A-TIM (green, PDB entry 2vek) and PGA to A-TIM (grey; PDB entry 2vel) in the closed loop 6/loop 7 active site. The hydrogen bonds between the carboxylate O atom of glycolic acid (GOA) and Gly173 N (loop 6) and Ser213 N (loop 7) are shown as dotted lines. |