Figure 1
(a) Structure predictions for S. cerevisiae Tho1 by Phyre and JPred. The solution structures of the SAP domains and C-terminal domains determined are shown below the predictions. (b) Sequence alignment of S. cerevisiae Tho1 compared with sequences from Kluyveromyces lactis, Ashbya gossypii, Vanderwaltozyma polyspora, Lodderomyces elongisporus, Candida albicans and Meyerozyma guilliermondii. Residues with high sequence similarity and identity are shown in closed boxes, with basic, acidic and aliphatic residues coloured blue, red and grey, respectively. |