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Figure 4
The hydrophobic patch on the outer surface of the β-sheet of the hEAG N-PAS domain. (a) Residues on the hydrophobic patch mediating intermolecular interaction. The side chains are shown in stick representation. (b) The hydrophobic patch on the surface of the structure of the hEAG N-PAS domain. The hydrophobic region is shown in white. (c) Crystal contacts formed by the hydrophobic patch between molecules A and D and molecules C and E. The hydrophobic contacts are shown in white. |