Figure 1
Sequence alignment between DHX15 and Prp43. A sequence alignment of DHX15 from human (DHX15_HUMAN), mouse (DHX15_MOUSE) and Drosophila melanogaster (DHX15_DROME) and of Prp43 from Saccharomyces cerevisiae (PRP43_YEAST) and Chaetomium thermophilum (PRP43_CHATD) is shown. The sequences were derived from UniProt (https://www.uniprot.org/) and were aligned using CLUSTALW (https://www.genome.jp/tools/clustalw/). The figure was prepared using ESPript3 (https://espript.ibcp.fr/ESPript/cgi-bin/ESPript.cgi; Robert & Gouet, 2014). The secondary structure of human DHX15 is shown at the top of each block. The residues involved in the interaction with ssRNA in ctPrp43 (Tauchert et al., 2017) are highlighted with black stars. |