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Figure 3
Stereo images of short modifications of Arg8 superimposed on the AHA-linked meditope (yellow) with the corresponding SPR sensograms. (a) n-Butyl extension of Arg8 (green) does not result in overall changes to the meditope, but threads through to the other side of the cetuximab Fab. Pro9, Leu114 and Pro155 HC are highlighted in light red. (b) The n-octyl extension (brown) of Arg8 points away from the Fab and positions the chain between Pro155 and Thr157 in the heavy chain and Asn41 in the light chain.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 73| Part 12| December 2017| Pages 688-694
https://doi.org/10.1107/S2053230X17016272
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