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Figure 5
Half-lives of Arg8 variant meditope–cetuximab interactions calculated using the formula t = ln(2)/kd. The off-rate of bimolecular interactions is independent of peptide/Fab concentration. All data were collected at 25°C in HBS-EP+ buffer pH 7.4. Unmodified, AHA-linked meditope with no modifications to Arg8; nBu, N-(n-butyl)arginine variant; nOc, N-­(n-octyl)arginine variant; PrNH2, N-(3-aminopropyl)arginine variant; PrOH, N-(3-hydroxypropyl)arginine variant; EtCOOH, N-(carboxy­ethyl)arginine variant.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 73| Part 12| December 2017| Pages 688-694
https://doi.org/10.1107/S2053230X17016272
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